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Meharry Medical College - Faculty
School of Medicine Faculty School of Dentistry Faculty School of Graduate Studies and Research Faculty Home

Derrick Beech, M.D.
Professor & Chair


Surgery

(615) 327-6274
George Hubbard Hospital (Old Hospital)
4th Floor
1005 Dr. D.B. Todd Boulevard
Nashville, TN 37208

dbeech@mmc.edu

CV or Bio (PDF)


 
Professional Education

 

 
Research Interests

 

 
Selected Publications

Flemming PK, Dedman AM, Xu SZ, Li J, Zeng F, Naylor J, Benham CD, Bateson AN, Muraki K, Beech DJ.  Sensing of lysophospholipids by TRPC5 calcium channel. J Biol Chem. 2005 Dec 20; [Epub ahead of print]

Cheong A, Wood IC, Beech DJ.  Less REST, More Vascular Disease?: Regulation of Cell Cycle and Migration of Vascular Smooth Muscle Cells.Cell Cycle. 2006 Feb 9;5(2) [Epub ahead of print]

Beech DJ, Cheong A.  Potassium channels at the beginnings of cell proliferation. J Physiol. 2005 Nov 17; [Epub ahead of print]

Beech DJ.  Ions in smooth muscle, now and then. J Physiol. 2005 Nov 10; [Epub ahead of print]
Cheong A, Bingham AJ, Li J, Kumar B, Sukumar P, Munsch C, Buckley NJ, Neylon CB, Porter KE, Beech DJ, Wood IC.  Downregulated REST transcription factor is a switch enabling critical potassium channel expression and cell proliferation. Mol Cell. 2005 Oct 7;20(1):45-52.

Xu SZ, Zeng F, Lei M, Li J, Gao B, Xiong C, Sivaprasadarao A, Beech DJ.  Generation of functional ion-channel tools by E3 targeting. Nat Biotechnol. 2005 Oct;23(10):1289-93. Epub 2005 Sep 18.

Beech DJ.  Emerging functions of 10 types of TRP cationic channel in vascular smooth muscle. Clin Exp Pharmacol Physiol. 2005 Aug;32(8):597-603.

Madan AK, Barden CB, Beech B, Fay K, Sintich M, Beech DJ.  Multivariate analysis of factors associated with smoking cessation in women. J La State Med Soc. 2005 Mar-Apr;157(2):112-5.

Beech DJ.  TRPC1: store-operated channel and more. Pflugers Arch. 2005 Oct;451(1):53-60. Epub 2005 Jun 18.

Xu SZ, Zeng F, Boulay G, Grimm C, Harteneck C, Beech DJ.  Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect. Br J Pharmacol. 2005 Jun;145(4):405-14.

Beech DJ, Cheong A, Rusch NJ.  Regulation of arterial tone by KV1 potassium channels. Circ Res. 2005 Apr 1;96(6):e58. No abstract available.

Bergdahl A, Gomez MF, Wihlborg AK, Erlinge D, Eyjolfson A, Xu SZ, Beech DJ, Dreja K, Hellstrand P.  Plasticity of TRPC expression in arterial smooth muscle: correlation with store-operated Ca2+ entry. Am J Physiol Cell Physiol. 2005 Apr;288(4):C872-80. Epub 2004 Nov 23.

Beech DJ, Muraki K, Flemming R.  Non-selective cationic channels of smooth muscle and the mammalian homologues of Drosophila TRP. J Physiol. 2004 Sep 15;559(Pt 3):685-706. Epub 2004 Jul 22. Review. Erratum in: J Physiol. 2004 Nov 1;560(Pt 3):949.

Zeng F, Xu SZ, Jackson PK, McHugh D, Kumar B, Fountain SJ, Beech DJ.  Human TRPC5 channel activated by a multiplicity of signals in a single cell. J Physiol. 2004 Sep 15;559(Pt 3):739-50. Epub 2004 Jul 14. Erratum in: J Physiol. 2004 Nov 1;560(Pt 3):950.

Beech DJ, Long AB, Long WP.  Dermatofibrosarcoma protuberans and breast cancer: genetic link or coincidental association? Am Surg. 2004 Jun;70(6):543-5.

Beech DJ, Harb W, Reed J.  Nodular melanoma of the face: a rare finding in African Americans. Am Surg. 2004 Apr;70(4):294-7.

Fountain SJ, Cheong A, Flemming R, Mair L, Sivaprasadarao A, Beech DJ.  Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle. J Physiol. 2004 Apr 1;556(Pt 1):29-42. Epub 2004 Jan 23.

Bergdahl A, Gomez MF, Dreja K, Xu SZ, Adner M, Beech DJ, Broman J, Hellstrand P, Sward K.  Cholesterol depletion impairs vascular reactivity to endothelin-1 by reducing store-operated Ca2+ entry dependent on TRPC1. Circ Res. 2003 Oct 31;93(9):839-47. Epub 2003 Oct 9.

Madan AK, Aliabadi-Wahle S, Beech DJ.  Physicians-in-training recommendations for prophylactic bilateral mastectomies. Breast J. 2003 Sep-Oct;9(5):397-402.

Madan AK, Colbert PM, Beech B, Beech DJ.  Effect of a short structured session on medical student breast cancer screening knowledge. Breast J. 2003 Jul-Aug;9(4):295-7.