Dineo Khabele, M.D.
Director, Gynecologic Oncology & Women’s Cancer Research Laboratory
Assistant Professor

Obstetrics and Gynecology

(615) 327-6284
Fax (Fax)
1005 Dr. D.B. Todd Boulevard
Hubbard Hospital
4th Floor
Nashville, TN  37208

dkhabele@mmc.edu

CV or Bio (PDF)

1989 Columbia College, Columbia University B.A. - Premedical Studies and Political Science
1994 M.D. - College of Physicians and Surgeons, Columbia University

Inflammatory Genes and Molecular Alterations in Ovarian Cancer.
Primary focus is on inflammatory genes COX-1 and TNFalpha in the development and progression of ovarian cancer. Another focus is the role of HDACs as targets for prevention and treatment of ovarian cancer.

Gorelick C, Lopez-Jones M, Goldberg GL, Romney SL, Khabele D. Coenzyme Q10 and lipid-related gene induction in HeLa cells. Amer J Obstet Gynecol: 190: 1432-4, 2004.

Khabele D, Lopez-Jones M, Yang W, Arango D, Gross SJ, Augenlicht L, Goldberg G. Tumor Necrosis Factor-α Related Gene Response to Epothilone B. Gynecol Oncol: 93: 19-26, 2004.

Mani S, McDaid H, Hamilton A, Hochster H, Cohen MB, Khabel(l)e D, Griffin T, Lebwhol DE, Liebes L , Muggia F, Horwitz SB. Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of Epothilone B, in solid tumors. Clin Cancer Res 10:1289-98, 2004.

Sood B, Jones J, Gupta S, Khabele D, Guha C, Runowicz C, Goldberg G, Fields A, Anderson P, Vikram B. Patterns of failure after the multimodality treatment of uterine papillary serous carcinoma. Int J Radiat Oncol Biol Phys; 57: 208-16, 2003.

Huang G, Einstein M, Khabele D, Goldberg, GL. Serum Biomarkers for Epithelial Ovarian Cancer. Women’s Oncology Review; 3: 117-22, 2003.

Khabele D, Runowicz CD, Fields AL, Anderson PS, Goldberg, GL. Evaluation of low-dose intraperitoneal interferon-alpha for palliation of ascites in patients with non-ovarian gynecologic malignancies. Gynecol Oncol; 89: 420-3, 2003.

Khabele D, Runowicz CD. Genetic counseling, testing and screening for breast and ovarian cancer: practical and social considerations. Curr Womens Health Rep; 2:163-9, 2002.

Gross SJ, Ferreira JC, Morrow B, Dar P, Funke B, Khabele D, Merkatz I. Gene expression profile of trisomy 21 placentas: A potential approach for designing noninvasive techniques of prenatal diagnosis. Am J Obstet Gynecol; 187(2):457-62, 2002.

Khabele D, Chasen S. Cardiac tamponade: An unusual presentation of advanced breast cancer in a pregnant woman. J Reprod Med, 44: 989-91, 1999.

Xiao E, Xia L, Shanen D, Khabele D, Ferin M. Stimulatory effects of interleukin-induced activation of the hypothalamo-pituitary-adrenal axis on gonadotropin secretion in ovariectomized monkeys replaced with estradiol. Endocrinol 135:2093-2098, 1994.