Ifeanyi Arinze, Ph.D.
Professor
Department of Cardiovascular Biology
Department of Biomedical Sciences

(615) 327-6586
WBS, Room 2103
1005 Dr. D.B. Todd Boulevard
Nashville, TN  37208

iarinze@mmc.edu

Lab URL

CV or Bio (PDF)

Ph.D. in Nutr. Biochemistry, Department of Biochemistry, University of Illinois, Urbana, 1972.

Dr. Arinze's laboratory is interested in the signal transduction mechanisms by which hormones regulate a variety of metabolic processes. Current studies are focused on the ontogeny and regulation of the developmental expression of G-proteins using cultured hematopoietic cells to study molecular mechanisms regulating expression of G-proteins.

Dr. Arinze is currently a member of the editorial board of the Journal of Biological Chemistry.

Kawai Y, Arinze IJ.  Valproic acid-induced gene expression through production of reactive oxygen species.Cancer Res.; 66:6563-9, 2006

Arinze IJ, Kawai Y.  Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements. J Biol Chem. 2005;280 :9786-95.

Croniger CM, Millward C, Yang J, Kawai Y, Arinze IJ, Liu S, Harada-Shiba M, Chakravarty K, Friedman JE, Poli V, Hanson RW. Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta have an attenuated response to cAMP and impaired carbohydrate metabolism. J Biol Chem, 276, 629-638, 2001

Yang J, Kawai Y, Hanson RW, Arinze IJ. Sodium butyrate induces transcription from the G alpha(i2) gene promoter through multiple Sp1 sites in the promoter and by activating the MEK-ERK signal transduction pathway. J Biol Chem, 276, 25742-25752, 2001