RECENT PUBLICATIONS

Al-Hendy A  and Salama A. Salama. A Functional Polymorphism in Catechol-O-Methyl Transferase Gene Explains Increased Risk of Uterine Leiomyomas in Black Americans. J Soc Gynecol Invest  2006. 13: 136-144.

Al-Hendy A. and Salama S. Gene therapy and uterine leiomyoma: a review. Human Reproduction updates, 2006 12: 385-400.

Salama S., Shu-Leong Ho, Hui Q. Wang, Jukka Tenhunen, Carola Tilgmann, and Al-Hendy A. Hormonal Regulation of Catechol-O-Methyl  Transferase Activity in Uterine Leiomyoma. Fertility & Sterility, 2006, 86: 259-262.

Al-Hendy A, Salama S. Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans. Fertility & Sterility, 2006, 86: 686-693.  

Al-Hendy A, Wang H, Copland J. Estrogen and progesterone receptors expression in
the endocervix. Implications for hormone replacement therapy after subtotal
hysterectomy. Middle East Fertility Society J 2006, 11 (3): 216-221.

Salama Salama, Abdelhakim Ben Nasr, Raghvendra K. Dubey,and Al-Hendy A. Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: A potential medicinal treatment for uterine fibroids. J Soc of Gynecol Investig  2006 Dec, 13 (8): 542-50.

Melissa J. Wentz, Robert Garfield, Mohamed Jamalludine and Ayman Al-Hendy. Hormonal Regulation of Catechol-O-Methyltransferase Expression in Human Myometrial Cells. Obstetrics & Gynecology 2006 Dec;108(6):1439-47

William W. Au, Salama Abdou-Salama, Carlos H. Sierra-Torres, Ayman Al-Hendy Environmental risk factors for prevention and molecular intervention of cervical cancer. Int J Hyg Environ Health. 2006 Dec 6; [Epub ahead of print].

Salama S, Kamel M, Christman G, Wang H and Al-Hendy A. Gene Therapy of Uterine Fibroids: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells. 2006. Obstetrics Gynecologic Investigations 2007, 63 (2): 61-70.

William W. Au, Salama Abdou-Salama, Al-Hendy, A. Inhibition of growth of cervical cancer cells using a dominant negative estrogen receptor gene. Gynecologic  Oncology 2007 Feb; 104(2): 276-80.

Fang Lu, Monica Longo, Esther Tamayo, William Maner, Ayman Al-Hendy, Garland D. Anderson, Gary D. V. Hankins, George R. Saade. The Effect of Over-expression of sFlt-1 on Blood Pressure, and the Occurrence of Other Manifestations of Preeclampsia, in Unrestrained Conscious Pregnant Mice. Am J Obstet Gynecol 2007 Apr;196(4):396.e1-7;

Essam R. Othman, salama S, Ismail N, and Ayman Al-Hendy. Gene Therapy of Endometriosis: Adenovirus mediated Expression of Dominant Negative Estrogen Receptor induces Apoptosis in Human Endometriotic Cells. Fertility & Sterility 2007 March 6; [Epub ahead of print]

Kamel M, Salama S, and Al-Hendy A. Adenovirus expressing Cyclooxgenase-2 antisense down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Therapy, 2007 (5), 1-10

Sana M Salih, Salama A Salama, Mohammad Jamaluddin, Manubai Nagamani and Ayman Al-Hendy. Cyclic variations of Catechol-O-Methyl Transferase (COMT) Expression in Human Endometrium and hormonal regulation of COMT in Human Stromal Endometrial Cell line. Fertility & Sterility 2007 April 4; [Epub ahead of print].

Sana M Salih, Manubai Nagamani, Antonie Duleba and Ayman Al-Hendy. Reduced Levels of Urinary 2 Hydroxy Estrogens in Polycystic Ovary Syndrome. J Clin Endocrinol Metab  2007 August; 92(8) 3285-91.

Essam El-Din R. Othman, Daniela Hornung, Hosam T. Salem, Essam A. Khalifa Tarek H. El-Metwally and Ayman Al-Hendy. Serum cytokines as potential bio-markers for non-surgical prediction of endometriosis. Eur J Ob Gyn Reprod Biol  2007 Jun 18; [Epub ahead of print]

Saed G, Al-Hendy A. Salama S, and Diamond M. Gene therapy of peritoneal adhesions: Adenovirus expressing COXII-antisense induce apoptosis in adhesion but not in normal peritoneal fibroblasts. Fertility & Sterility 2007 July 9; (Epub ahead of print)

Salama S., and Ayman Al-Hendy. Hormonal Regulation of Catechol-O-Methyl  Transferase Activity in two breast cancer cell lines. J Steroid Biochemistry Mol Biol 2007 June 30; (Epub ahead of print)

Sana Salih, Mohammad Jamaluddin, Salama A. Salama, Amin Fadel, Manubai Nagamani and Ayman Al-Hendy. Regulation of Catechol-O-Methyl Transferase Expression in Granulosa Cells: A Unifying Model for Follicular Atresia in Polycystic Ovary Syndrome. Fertility & Sterility 2007 July 3; (Epub ahead of print).

Hassan M, Salama S, and Al-Hendy A. Gene Therapy of Uterine Fibroids: Dominant negative estrogen receptor attenuate global estrogen-dependent gene activation in Leiomyoma Cells. J Clin Endocrinol Metab 2007 July 17; (Epub ahead of print).

Melissa J. Wentz, Leili Shi, Shao-Qing Shi, Salama A. Salama, Robert E Garfield and Ayman Al-Hendy. Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and increases cervical resistance to stretch in pregnant rats.  Reproduction 2007 Dec, 134 (6): 831-9.

Sana M Salih, Salama A Salama, Mohammad Jamaluddin, Amin A. Fadl, Manubai Nagamani, and Al-Hendy A. Regulation of Catechol-O-Methyl Transferase (COMT) Expression in Endometrial Cancers Cells: Distinctive Role of Progesterone Receptor Isoforms. J Reproductive Sciences (In Press)

Zhang Dong, Zoma Willie, Fouad Hala, Salama Salama, and Ayman Al-Hendy.  Expression of Stem & Germ Cells Markers within Non-Follicle Structures in Ovaries from Adult Mice. J Reproductive Sciences (In Press)

Ghadami M, Salama S, Chilvers R, and Al-Hendy A. Toward gene therapy of premature ovarian failure: Adenovirus expressing human FSH receptor corrects the Finnish C566T mutation. Mol Human Reproduction (In Press)

Hassan M, Curiel D, and Al-Hendy A. Towards Gene Therapy of Uterine Fibroids: Targeting Adenovirus to human leiomyoma cells. Human Reproduction (In Press)

Samar Azab, Salama Salama, Ashraf Abdel-Naim, Amani Khalifa, Ebtehal El-Demerdash, Al-Hendy A. Can 2-methoxyestradiol modulate Multidrug resistance? Role of 2-methoxyestradiol in chemosensitizing resistant breast cancer cells. Breast Cancer Research & Treatment (In Press)

Samar Azab, Salama Salama, Memy Hassan, Amani Khalifa, Ebtehal El-Demerdash, Hala Fouad, Ayman Al-Hendy, Ashraf Abdel-Naim. 2-Methoxyestradiol: a promising modulator of multidrug resistance in human breast tumor xenograft. Journal of Cancer Chemotherapy & Pharmacology (In Press)

Dr. Gloria Richard-Davis
Clark R, Murphy, M, Theall, K, Richard-Davis, G, . Alternative Pathways to Parenthood.
John Hopkins Publishing, publication pending 2007.

Conception: A Comprehensive Guide to Fertility, Written by the Experts. Insight
International Press, LLC, publication pending 2007.

Goserelin Acetate (Zoladex) 10.8 mg Plus Iron Prior to Surgery Is Beneficial to
Premenopausal Women with Iron-Deficiency Anemia Due to Uterine Leiomyomas:
Results from a Phase III, Randomized, Multicenter, Double-Blind, Controlled Trial (11-
329), Clinical Therapeutics, pending 2007.