Targeting Adenovirus for Gene Therapy of Uterine Leiomyoma
Researcher: Ayman Al-Hendy, M.D., Ph.D., FRCSC, FACOG, CCRP
Funding Source: National Institute of Child Health/Human Dev. (NICHD)
Project Summary: For women with symptomatic fibroids who want to preserve fertility, there are currently limited conservative treatment options that will treat their fibroids without compromising subsequent chances of achieving a healthy pregnancy. In this research we are aiming to develop an improved gene therapy approach for effective and safe localized treatment of uterine fibroids. Additionally it will enhance our understanding of the role of steroid hormones in pathogenesis of uterine fibroids using unique in vivo model systems.