Current Clinical Research Center Studies

 Title of Study

Principal Investigator

Focus

Racial Differences in Circulating Sex Steroids and Their Effect on Bone and Ovarian Function

Valerie Montgomery-Rice, MD

Women’s Health
For more information:
Joy Vassall
615-327-5765

The Effects of Combination Therapy with Lifestyle Intervention and Metformin in Females with Poly cystic Ovary Syndrome

Gwinnett Ladson, MD

Women’s Health
For more information:
Barbara Dailey
615-327-5569

The Effects of Oral Contraceptives and Endogenous Sex Steroids on Uterine Leioymyomas

Stephanie Sweet, MD

Women’s Health
For more information:
Joy Vassall
615-327-5765

A 12-Month, Open Label, Multi center Study to Evaluate the Safety of a 1.3 g Oral Dose of a New Modified-Release Tranexamic Acid Formulation Administered Three Times Daily

Valerie Montgomery-Rice, MD

Women’s Health
For more information:
Joy Vassall
615-327-5765

Hypertension and Oxidative Stress and Race

Zhongmao Guo, Ph.D.

Heart Disease
For more information:
Joan Ross
615-327-6884

AASK Cohort Grant/Genetic Component

Marquetta Faulkner, MD

Kidney Disease
For more information:
Virginia (Ginger) Sanford
615-327-6007

Study of Heart and Renal Protection (SHARP)

Marquetta Faulkner, MD

Heart and Kidney Disease
For more information:
Virginia (Ginger) Sanford
615-327-6007
-or-
Joan Ross
615-327-6884

Pharmacogenomics of Arrhythmia and Anticoagulants

Michael Floyd, MD

Heart Disease
For more information:
Lavenia Crutcher
615-327-5651

A 52 Week Multi center, Randomized, Double-Blind, Parallel Group Study to Evaluate the Efficacy of Lotrel and Benazepril Hydrochlorothiazide in the Regression of Left Ventricular Hypertrophy by Magnetic Resonance Imaging in Patients with High Risk Hypertension (ALIVE)

Henry Okafor, MD

Heart Disease
For more information:
Lavenia Crutcher
615-327-5651

Pharmacogenomics of Arrhythmia Therapy - Atrial Fibrillation (AF) (NIH HL755266)

Michael Floyd, MD

Heart Disease
For more information:
Lavenia Crutcher
615-327-5651

Value of Left Ventricular Filling Pressures Derived by Echocardiography for the Prediction of Heart Failure Readmissions (AETNA Foundation)

Henry Okafor, MD

Heart Disease
For more information:
Lavenia Crutcher
615-327-5651

An eight week, randomized, double-blind, parallel-group, multi center study to evaluate the efficacy and safety of the combination of Aliskiren / Valsartan / HCTZ (300/320/25 mg), compared to the combinations of Aliskiren / HCTZ (300/25 mg) and Valsartan / HCTZ (320/25 mg) in patients with essential hypertension not adequately responsive to HCTZ 25 mg

Marquetta Faulkner, MD

Heart and Kidney Disease
For more information:
Virginia (Ginger) Sanford
615-327-6007

PC010092 - Dietary Fat and Vitamin E in Prostate Cancer Risk Among African Americans and Africans:  A Case Control Study

Flora Ukoli, DPH, MPH

Prostate Cancer
For more information:
Flora Ukoli
615-327-5653

Selenium and Vitamin E in Prostate Cancer

Emeka Ikpeazu, MD

Prostate Cancer
For more information:
Flora Ukoli
615-327-5653

Evaluation of Serotype-Specific Immunity to Streptococcus Pneumonia in Adults

Vladamir Berthaud, MD

HIV/AIDS
For more information:
Lavenia Crutcher
615-327-5651

A Randomized, Double-blind, Placebo-Controlled, Multi center, Parallel-Group phase 3 Study to Determine the Efficacy & Safety of Retigabine (1200mg/day) Used as Adjunctive Therapy in Refractory Epilepsy Patients with Partial-Onset Seizures (Valeant Research & Development VRX-RET-E22-301)

Pradumna Singh, MD

Epilepsy
For more information:
Virginia (Ginger) Sanford
615-327-6007
Audrey Sparkman
615-327-5611

F0000A Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial "PREADVISE" (NIH/NIA)

Chukwuemeka Ikpeazu, MD

Alzheimer’s Disease
For more information:
Joan Ross
615-327-6884

A Phase IV, Non-Randomized, Open-Label Trial Evaluating the Safety of the 625mg Formulation of Viracept When Administered to HIV-Infected Women During Pregnancy/Protocol #A4301017

Janice E. Whitty, M.D.

HIV/AIDS
For more information:
Keisha Ashmeade
615-327-5676

Randomized Controlled Trial of the Safety and Efficacy of Pneumococcal Conjugate Vaccine in HIV Infected Adults

Vladamir Berthaud, MD

HIV/AIDS
For more information:
Lavenia Crutcher
615-327-5651

A Phase III, Multi center, 52-Week, Randomized, Double-Blind, Placebo-Controlled Study of the Clinical Efficacy and Safety of ICA 17043 with or without Hydroxyurea Therapy in Patients with Sickle Cell Disease Who Have Had Two Acute Sickle-Related Painful Crises within the Preceding 12 Months

Steven Wolff, MD

Sickle Cell
For more information:
Lavenia Crutcher
615-327-5651

Nursing Partnership for Community Health Improvement

Lavenia Crutcher, BSN, MSPH

Community Outreach
For more information:
Lavenia Crutcher
615-327-5651