The Center for Women 's Health at Meharry was created in 2003 as a multi-disciplinary health facility to conduct research to improve outcomes in the elimination of health disparities, to train medical students and residents in women 's health issues, and to provide premier healthcare services for women.  The Center is designed to become a nationally recognized model for the treatment and research of issues that impact women 's health.

CWHR was the brain child of Valerie Montgomery Rice, M.D. Chair of Obstetrics and Gynecology in 2003. Others among the founding executive leadership included PonJola Coney, M.D. - Senior Vice President for Health Affairs and Dean of the School of Medicine and Denese Shervington, M.D., chair of psychiatry, Co-Director of the Center.